… of 17β-estradiol (E2) and 5α-dihydrotestosterone (DHT) on the apoptotic signaling pathways
of immature rat … For that we chose key points of the apoptotic pathway that interact with the …

… intermediate potent androgen 5α-dihydrotestosterone (DHT), … Here, we have characterized
the influence of 17β-estradiol (E… ERβ, on the other hand, has been localized to rat Sertoli cells…

… and testosterone signaling pathways in Sertoli cell proliferation… process, for example 5α-dihydrotestosterone
(DHT) regulates … cell cycle arrest by interacting with 17β-estradiol (E2) (106). …

… The cAMP/PKA signaling pathway participates in Sertoli cell differentiation, SSC self-renewal …
in immature rat SCs activates the caspase 9 mediated intrinsic apoptotic pathway [118]. …

… In these cells, 17β-estradiol (E2) at physiological concentration … In addition, the 5α-dihydrotestosterone
metabolite 5α-… , and lead to activation of the MAPK3/1 signaling pathway [56]. In …

… these signaling pathways are hormone-dependent and cell-… (T) and 17β-estradiol (E 2
) by Leydig cells, provides a … hormonal control by insulin, E 2 and 5α-dihydrotestosterone (…

… site from Sertoli cells in the immature testis to Leydig cells in … , and as this apoptosis can be
blocked by 17β-estradiol, we … a novel nongenomic signaling pathway through ERs located …

… has been detected in Leydig cells, Sertoli cells and germ cells, notably in spermatogonia, …
is converted into 5α-dihydrotestosterone by 5α-reductase (SRD5A1), or into 17β-estradiol by …

… As SCs apoptotic signaling is a hormonally regulated process, we hypothesized … Regulation
of apoptotic signaling pathways by 5𝛼-dihydrotestosterone and 17𝛽estradiol in Immature rat …

… hormones on key points of cultured rat SCs glycolytic pathway. We used primary cultures
of immature rat SCs treated with 17β-estradiol (E2) or 5α-dihydrotestosterone (DHT). The …